Wednesday, May 24, 2017

(LML) Taiwan's LoSheng Hospital

 

Leprosy Mailing List – May 24,  2017

Ref.:   (LML)  Taiwan's LoSheng Hospital

From:  Eric Lee Wan, Baltimore, USA


 

 

Dear Pieter

 

My name is Eric Wan from Johns Hopkins, and I have been involved in Hansen's research (focusing on surgery) for the past several years, working mostly in Ecuador. I am now traveling through Taiwan, and would like to reach out to LML and see if anyone here has connections with the LoSheng Hospital (which used to be the Hansen's Disease hospital) outside of Taipei. My ethnicity is Taiwanese American, so a visit to LoSheng is very important to me personally and professionally. Thank you for your time and attention!

 

Eric Wan

--

Eric Lee Wan, BS

Consultant (Community Health & Research)
Fundación Padre Damian
Guayaquil, Ecuador
+593 4-228-6649

Research Affiliate
Department of Plastic and Reconstructive Surgery,
Johns Hopkins University School of Medicine
Baltimore, Maryland, USA

Google Voice:
+1 (678) 744-9361
USA Cell: 
+1 (240) 899-1181
Ecuador Cell: 
+593 (96) 804-5383
Colombia Cell: +57
(313) 780-6653
Skype: ericleewan
https://www.linkedin.com/in/ericleewan


LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com

 


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Friday, May 19, 2017

(LML) InfoNTD Information on cross-cutting issues in NTDs May 2017

 

Leprosy Mailing List – May 19,  2017

Ref.: (LML)  InfoNTD Information on cross-cutting issues in NTDs May 2017

From:  Ilse Egers, Amsterdam, the Netherlands


 

Dear Pieter,

This newsletter provides you with a selection of news items and recent publications on cross-cutting issues in NTDs. Our starting point is to add articles covering a wide variety of issues. Unfortunately, this is not always possible due to a limited diversity in and shortage of articles on cross-cutting issues and NTDs.

Feel free to contact us (
infontd@leprastichting.nl) with any questions or to receive the full text versions if a link to the full text is not included. Our document delivery service is free!

Kind regards,
 
Ilse Egers
InfoNTD Information officer

 

 

News

 

 

The Lancet Global Health Blog
By Roy Anderson & Alison Bettis
The top five investments we should be making to tackle NTDs.
Read more

South East Asia pledge to intensify efforts against neglected tropical diseases
26 April 2017 | Jakarta | New Delhi
Member States of the World Health Organization's South East Asia Region have resolved to accelerate work in defeating five widespread neglected tropical diseases by 2020.
Read more

 

 

New publications

 

 

Yaws resurgence in Bankim, Cameroon: The relative effectiveness of different means of detection in rural communities.
Boock AU, Awah PK, Mou F. et al. PLoS Negl Trop Dis. 2017; 11(5):e0005557.
Abstract The five interventions for detecting yaws had a synergistic effect and proved to be valuable components of a yaws eradication program. Well planned, culturally sensitive mass outreach educational programs accompanied by school-based programs proved to be particularly effective in Bankim. Including yaws detection in a Buruli Ulcer outreach program constituted a win-win situation, as the demonstration effect of yaws treatment (rapid cure) increased confidence in early Buruli ulcer treatment. Mass outreach programs functioned as magnets for both diseases as well as other kinds of chronic wounds that future outreach programs need to address.
Download PDF


Associations between selective attention and soil-transmitted helminth infections, socioeconomic status, and physical fitness in disadvantaged children in Port Elizabeth, South Africa: An observational study.
Gall S, Müller I, Walter C, Seelig H. et al. PLoS Negl Trop Dis. 2017; 11(5):e0005573.
Abstract The present study examines how socioeconomic status (SES), parasitic worm infections, stunting, food insecurity, and physical fitness are associated with selective attention and academic achievement in school-aged children. Soil-transmitted helminth infections and low physical fitness appear to hamper children's capacity to pay attention and thereby impede their academic performance. Poor academic achievement will make it difficult for children to realize their full potential, perpetuating a vicious cycle of poverty and poor health.
Download PDF


Improving drug delivery strategies for lymphatic filariasis elimination in urban areas in Ghana.
Biritwum N-K, Garshong B, Alomatu B et al. PLoS Negl Trop Dis. 2017; 11(5):e0005619.
Abstract The study was carried out in three phases: pre-intervention, intervention and post-intervention phases, to assess the profile of the urban areas and identify reasons for poor treatment coverage using both qualitative and quantitative research methods. The outcomes from the study revealed that, knowledge, attitudes and practices of community members to MDA improved slightly from the pre-intervention phase to the post-intervention phase, in the districts where the interventions were readily implemented by health workers. Many factors such as adequate leadership, funding, planning and community involvement, were identified as being important in improving implementation and coverage of MDA in the study districts. Implementing MDA in urban areas therefore needs to be given significant consideration and planning, if the required coverage rates are to be achieved. This paper, presents the recommendations and strategies for undertaking MDA in urban areas.
Download PDF


Guidelines for use of narrative survey instruments to improve MDA for lymphatic filariasis elimination.
Krentel A, Lynam T. Reflecting Society. 2017. Report.
Abstract Literature examining reasons why recipients take drugs offered during mass drug administration (MDA) for the elimination of lymphatic filariasis (LF) suggests that few knowledge indicators explain recipients’ compliance with treatment.
These guidelines outline the use of a novel tool and approach in public health research that places an individual’s situated or contextualised experience at the core of the research. Instead of asking about knowledge, this survey instrument asks individuals to recount their most recent experience with MDA and then asks a series of questions about that narrative.
Download PDF


A practical approach for scaling up the alternative strategy for the elimination of lymphatic filariasis in Loa loa endemic countries - developing an action plan.
Kelly-Hope LA, Stanton MC, Zouré HGM, et al. Glob Health Res Policy. 2017.
Abstract We reviewed relevant data available to WHO and in the literature for LF-L. loa endemic countries to develop a simple method to support the scale-up of MDA to eliminate LF. A basic model has been developed. The model includes five practical steps, which comprise the development of a national filarial database and a simple classification system to help determine the mapping status and most appropriate treatment strategy. Steps are colour-coded and linked to a general decision tree, which is also presented. This model is simple to follow and will help LF elimination programmes develop an action plan and scale up the implementation of alternative treatment strategies.
Download PDF


Recognising the role of community-directed treatment and of women in the fight against NTDs.
Amazigo U, Crump A, Godal T. Lancet Glob Health. 2017.
No abstract.
Download PDF


Infectious Diseases of Poverty, the first five years.
Wang W, Chen J, Sheng H-F, Wang N-N. et al. Infect Dis Poverty. 2017; 6(1):96.
Abstract Although the focus in the area of health research may be shifting from infectious to non-communicable diseases, the infectious diseases of poverty remain a major burden of disease of global health concern. A global platform to communicate and share the research on these diseases is needed to facilitate the translation of knowledge into effective approaches and tools for their elimination. Based on the "One health, One world" mission, a new, open-access journal, Infectious Diseases of Poverty (IDP), was launched by BioMed Central in partnership with the National Institute of Parasitic Diseases (NIPD), Chinese Center for Disease Control and Prevention.
Download PDF


Integrating neglected tropical diseases into global health and development: Fourth WHO report on neglected tropical diseases. 2017. Report.
Abstract This fourth WHO report on neglected tropical diseases (NTDs) reviews the progress made towards achieving the Roadmap targets for 2020, noting the remaining challenges, then looks beyond 2020 to evaluate the changing global health and development landscape, considering the implications of integrating these diseases into the broader 2030 Agenda for Sustainable Development.
Download PDF


Disease ecology, health and the environment: a framework to account for ecological and socio-economic drivers in the control of neglected tropical diseases.
Garchitorena A, Sokolow SH, Roche B. et al. Philos. Trans. R. Soc. Lond. 2017; 372(1722).
Abstract We present a simple modelling framework to illustrate the relative role of ecological and socio-economic drivers of environmentally transmitted parasites and pathogens. Through the analysis of system dynamics, we show that periodic drug treatments that lead to the elimination of directly transmitted diseases may fail to do so in the case of human pathogens with an environmental reservoir. Control of environmentally transmitted diseases can be more effective when human treatment is complemented with interventions targeting the environmental reservoir of the pathogen. We present mechanisms through which the environment can influence the dynamics of poverty via disease feedbacks.
Read more


Modelling ecological and socioeconomic feedbacks of Buruli ulcer in sub-Saharan Africa: results from a field study in Cameroon.
Garchitorena A, Bonds MH, Ngonghala CN. et al. The Lancet. 2017; 389(Suppl 2).
Abstract We provide the first field evidence that the predominant transmission route from the aquatic ecosystem to human populations might be through direct inoculation of the bacteria into the skin in contaminated environments, contrary to the vector-borne transmission postulated in the past decade. Median force of infection in the set of model simulations that best fitted the data was more than 200 times higher for proxies of direct environmental transmission than for vector-borne transmission. Based on these results, we show theoretically that in contexts of high environmental risk, Buruli ulcer can cause economic inequalities at the population level, with disproportionate effects on the poorest socioeconomic groups due to disparities in vulnerability and health-care access.
Read more


Mycetoma: A global medical and socio-economic dilemma.
Fahal AH. PLoS Negl Trop Dis. 2017; 11(4):0005509.
No abstract.
Download PDF


The first "London Declaration": The Commonwealth and its neglected tropical diseases.
Hotez PJ, Damania A, Barua A. et al. PLoS Negl Trop Dis. 2017; 11(4):e0005321.
No abstract.
Download PDF


Risk factors for podoconiosis: Kamwenge District, Western Uganda.
Musenero M, Nanyunja M, Lali WZ. Am. J. Trop. Med. Hyg. 2017.
Abstract Podoconiosis, a noninfectious elephantiasis, is a disabling neglected tropical disease. In August 2015, an elephantiasis case-cluster was reported in Kamwenge District, western Uganda. We investigated to identify the disease's nature and risk factors. We defined a suspected podoconiosis case with the following associated symptoms: skin itching, burning sensation, plantar edema, lymph ooze, prominent skin markings, rigid toes, or mossy papillomata. A probable case was a suspected case with negative microfilaria antigen immunochromatographic card test (ruling out filarial elephantiasis). We conducted active case-finding. In a case–control investigation, we tested the hypothesis that the disease was caused by prolonged foot skin exposure to irritant soils. In conclusion, this reported elephantiasis is podoconiosis associated with prolonged foot exposure to volcanic soil. We recommended foot hygiene and universal use of protective shoes.
Download PDF


The global atlas of podoconiosis.
Deribe K, Cano J, Newport MJ, et al. Lancet Glob Health. 2017; 5(5): e477-e479.
Abstract The world stands on the edge of an historic public health success with the imminent eradication of dracunculiasis (guinea-worm disease) and polio. In 2016, only 25 human cases of dracunculiasis were reported from three countries, transmission of wild poliovirus was found in only three countries, and 37 cases of polio were reported worldwide. In addition to these achievements, there has been progress in the elimination of the little-known disease podoconiosis (endemic non-filarial elephantiasis).
Download PDF


Collaborating to develop joint water, sanitation and hygiene (WASH) and neglected tropical disease (NTD) sector monitoring: an expert consultation.
Waite RC, Woods G, Velleman Y, et al. Int Health. 2017. 1-11.
Abstract Taking forward outputs from global WASH and NTD Roundtables, we engaged experts in a consultative process of identifying measurable priority indicators for joint monitoring. Seven core measurable indicators emerged as priorities for inclusion in joint monitoring for the NTD sector. Our findings provide insight on the development and implementation of joint monitoring frameworks that can be integrated into existing programme level monitoring.
Read more


Psychosocial impact of scars due to cutaneous leishmaniasis on high school students in Errachidia province, Morocco.
Bennis I, Thys S, Filali H, et al. Infect Dis Poverty. 2017; 6(1):46.
Abstract The outbreak of CL due to Leishmania major in the Errachidia province in southeastern Morocco between 2008 and 2010 left many adolescents with permanent scar tissue on the face or other exposed body parts. We studied the psychosocial impact of CL on these young people. Almost 20% reported they had experienced a CL lesion and 87% said it could possibly or definitely lead to psychological consequences. The indelible CL scars lead to self-stigma and social stigma, and the emergence of negative psychological effects in this age group.
Download PDF


Engaging 'communities': anthropological insights from the West African Ebola epidemic.
Wilkinson A, Parker M, Martineau F, et al. Philos. Trans. R. Soc. Lond., B, Biol. Sci. 2017; 372(1721):1-7.
Abstract This article reflects on the nature of community engagement during the Ebola epidemic and demonstrates a disjuncture between local realities and what is being imagined in post-Ebola reports about the lessons that need to be learned for the future. We argue that to achieve stated aims of building trust and strengthening outbreak response and health systems, public health institutions need to reorientate their conceptualization of 'the community' and develop ways of working which take complex social and political relationships into account.
Download PDF


Community-directed mass drug administration is undermined by status seeking in friendship networks and inadequate trust in health advice networks.
Chami GF, Kontoleon AA, Bulte E, et al. Soc Sci Med. 2017.
Abstract In Mayuge District, Uganda, census-style surveys were conducted for 16,357 individuals from 3491 households in 17 villages. Praziquantel, albendazole, and ivermectin were administered for one month in community-directed MDA to treat Schistosoma mansoni, hookworm, and lymphatic filariasis. We investigated systematically missed coverage and noncompliance. CMDs were more likely to offer medicines, and to accurately administer the drugs as trained by the national control programme, to individuals with high friendship degree (many connections) and high friendship closeness centrality (households that were only a short number of steps away from all other households in the network).
Read more


Challenges of soil- transmitted Helminthiasis in some communities in Ondo state, Nigeria.
Akinseye FJ, Egbebi AO, Fadareo S. Int. J. Adv. Res. Biol. Sci. 2017; 4(3):164-171.
Abstract This study aimed at investigating the burden of soil-transmitted helminthiasis in some selected rural communities in Ondo State Nigeria. This study was carried out to determine the prevalence of human soil- transmitted helminthiasis. Out of the 928 samples collected from volunteers, 149 (16.05%) were infected. Among the risk factors, toilet and water resource facilities were the major sources of transmission. The result obtained justifies the current state of the poor hygiene level in relation to high occurrence rate of Soil-transmitted helminths among people living in the rural settings.
Download PDF


How to determine if a model is right for neglected tropical disease decision making.
Bartsch SM, Lee BY. PLoS Negl Trop Dis. 2017; 11(4):e0005457.
Abstract Mathematical and computational modeling can transform decision making for neglected tropical diseases (NTDs) if the right model is used for the right question. Modeling can help better understand and address the complex systems involved in making decisions for NTD prevention and control. However, all models, modelers, and modeling are not the same. Thus, decision makers need to better understand if a particular model actually fits their needs. Here are a series of questions that a decision maker can ask when determining whether a model is right for him or her.
Download PDF


Neglected tropical diseases: A proxy for equitable development and shared prosperity.
Engels D. PLoS Negl Trop Dis. 2017; 11(4):e0005419.
No abstract
Download PDF


PLOS Neglected Tropical Diseases: Ten years of progress in neglected tropical disease control and elimination … More or less.
Aksoy S, Hotez P. PLoS Negl Trop Dis. 2017; 11(4):e0005355.
Abstract This year PLOS Neglected Tropical Diseases (PLOS NTDs) celebrates its tenth anniversary following the publication of the first issue in 2007. In the decade since, PLOS NTDs has overseen enormous successes in NTD control and elimination. Here, we want to briefly review the ten year progress made towards the control or elimination of the diseases now identified by the WHO as NTDs.
Download PDF


The PLOS Neglected Tropical Diseases decade.
Bundy DAP, Hotez P. PLoS Negl Trop Dis. 2017; 11(4):e0005479.
No abstract.
Download PDF


Global coalition chips away at neglected tropical diseases.
Maxmen A. Nature. 2017; 544(7650):281-282.
No abstract.
Download PDF


 

 

Events

 

 

ISNTD d3
May 16-17, London, UK
The International Society for Neglected Tropical Diseases
ISNTD d3 will bring together experts from within drug discovery and clinical trials to drive the debate and foster new partnerships & alliances leading to tangible outcomes in terms of new therapies to combat these diseases.

Vector Borne Disease 5 Day Workshop
May 22-26, Dubai, United Arab Emirates
The MENTOR Initiative is now delighted to be able to offer a new training course designed specifically to strengthen the capacity of agencies to implement effective and coordinated vector borne disease control activities, either as a focus or as part of broader disease control activities.


LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com

 


Virusvrij. www.avast.com

Wednesday, May 10, 2017

(LML) Preventive measures for leprosy

Leprosy Mailing List – May 10,  2017

Ref.:  (LML)  Preventive measures for leprosy

 

From: Joel Almeida, London and Bombay 


 

Dear Pieter,

 

Esteemed colleagues on LML might be interested in this response to a thought-provoking recent article. 

 

Reference: Laura Gillini, Erwin Cooreman, Tanya Wood, Venkata Rao Pemmaraju, Paul Saunderson. Global practices in regard to implementation of preventive measures for leprosy. PLOS NTD. Published: May 4, 2017. https://doi.org/10.1371/journal.pntd.0005399

 

The authors state, "active case-finding activities have been reduced and it is likely that a significant number of incident cases are not being detected." This guess seems reasonable.

Most incident cases of leprosy are transient and self-healing. A permanent marker of disease can help indicate the underlying trend in the true incidence rate of all leprosy cases, even if transient cases are missed. Permanent physical damage, in the form of visible deformities, is such a marker. In India, the incidence rate of cases with visible deformity at diagnosis has doubled in the decade since 2005 (1). This strongly suggests a rising trend in the incidence rate of leprosy in India. India has well over half the world's new cases of leprosy.

The authors' hopes regarding post-exposure prophylaxis seem over-optimistic even by their own account of the epidemiology. If the infection spreads largely before treatment of the index case is started, then belated and truncated treatment of household contacts is unlikely to reduce the incidence rate. Even if it delays the onset of clinical signs in household contacts for a couple of years.

Two rounds of whole-population chemoprophylaxis with 3 drugs (rifampicin + ofloxacin + minocycline) had only a temporary impact on the incidence rate of leprosy on some small islands. (2) The incidence rate rose again subsequently. Therefore hopes about sustainably reducing the incidence rate by chemoprophylaxis among contacts of index cases might well prove to be over-optimistic. This might remain so even if delays in diagnosis were shortened.

Further, visitors to the homes of Indian leprosy patients already treated with powerful bactericidal drugs (multi-drug therapy, MDT) show an increased risk of developing the disease, compared to the risk in the local population.(3) This remains true even after the patients have apparently been "cured" by MDT. This increase in risk might well be manifested in household contacts after the concentration of single-dose rifampicin in their blood has declined to non-therapeutic levels.

M. leprae, when dried in the Indian shade, remain viable for up to 5 months (4). M. leprae ingested by amoebae remain similarly viable for at least 8 months (5). If an individual with low specific immunity comes into contact with such M. leprae, replication can resume. The cycle of transmission could then be maintained indefinitely even if M. leprae do not replicate outside hosts. The duration of extra-human survival may prove to be longer than 8 months, if more prolonged studies are undertaken. In Norway, a phenolic glycolipid specific to M. leprae was found in the environment decades after the last human case (6). It seems prudent to presume that dried M. leprae, which measure under 10 microns, can become airborne along with other dust. Single-dose chemoprophylaxis has only a transient effect, not offering sustained protection against such extra-human sources of infection.

A sustained reduction in the incidence rate of leprosy owing to chemoprophylaxis seems uncertain. Therefore it seems wise to treat it as a fervent hope rather than a firm promise. Meanwhile, those newly developing the disease need protection from permanent disfigurement. This requires the rebuilding of leprosy expertise. Trained mobile workers need pro-actively to visit patients and monitor their nerve function, so that anti-inflammatory treatment can be started before permanent disfigurement sets in. 

Over-optimistic hopes and promises have dealt blows to leprosy services in the past. Funding, talent and human resources have effectively been diverted away from leprosy. This has merely facilitated the spread of leprosy and its associated disfigurements. Such mistakes of over-optimism need not be repeated.


 

Joel Almeida

 

 


References

1) Central Leprosy Division, Government of India. NLEP Newsletter October–December 2016, Vol. 1, issue 5

2) Diletto C, Blanc L, Levy L. Leprosy chemoprophylaxis in Micronesia. Lepr Rev. 2000 Dec;71 Suppl:S21-3; discussion S24-5.

3) P. Vijayakumaran et al. Does MDT Arrest Transmission of Leprosy to Household Contacts? Int. J. Lepr. (1998) 66(2): 125-130.

4) Desikan KV, Sreevatsa. Extended studies on the viability of Mycobacterium leprae outside the human body. Lepr Rev. 1995 Dec;66(4):287-95.

5) Wheat HW et al. Long-term Survival and Virulence of Mycobacterium leprae in Amoebal Cysts. PLoS Negl Trop Dis. 2014 Dec; 8(12): e3405

6) Kazda J, Irgens L, Kolk A. Acid fast bacilli found in sphangnum vegetation of coastal Norway containing Mycobacterium leprae specific phenolic glycolipid-I.
Int J Lepr. 1990;58:353-357.

 


LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com

 


Virusvrij. www.avast.com

Tuesday, May 9, 2017

(LML) Infolep monthly overview of new publications on leprosy - May 2017

Leprosy Mailing List – May 9,  2017

Ref.:  (LML)  Infolep monthly overview of new publications on leprosy - May 2017

From:  Jiske Erlings, Amsterdam, the Netherlands


 

Dear friends and colleagues, 
 
Below you will find a selection of recent publications on leprosy and related subjects. Feel free to contact me (infolep@leprastichting.nl) to receive the full text versions if a link to the full text is not included or for assistance with your literature research. You are also invited to send us your publications on leprosy or material on leprosy in your language to include in the portal.

With kind regards,
 
Jiske Erlings
Infolep Information specialist

 

 

Highlighted publications

 

 

Integrating neglected tropical diseases into global health and development: fourth WHO report on neglected tropical diseases.
Geneva: World Health Organization. 2017
Download PDF

Special report on Neglected Tropical Diseases
Financial Times. 2017.
https://www.ft.com/neglected-tropical-diseases

Global Leprosy Strategy 2016–2020. Accelerating towards a leprosy-free world. Monitoring and Evaluation Guide.
New Delhi: World Health Organization, Regional Office for South-East Asia. 2017.
Download PDF

International textbook of leprosy.
Scollard DM, Gillis TP.
American Leprosy Missions. 2016.
Now online - with new chapters!

 

 

New publications

 

 

[Immunoreactivity of dendritic cells in foveolar lesions in borderline leprosy]
de Aarão TLS,  Botelho BS, Botelho GIS, et al.
Rev Pan-Amaz Saude. 2013 June;4(2):19-25
Download PDF


Modified simple decompression in the treatment of cubital tunnel syndrome: avoiding ulnar nerve subluxation.
Acioly MA, Soares AM, de Almeida ML, et al. Arq. Neuro-Psiquiatr. 2017.
Download PDF


"The legacy of thalidomide" - A multidisciplinary meeting held at the University of York, United Kingdom, on September 30, 2016.
Atkin K, Newbronner E, Vargesson N. Birth Defects Res. 2017 Mar 1;109(4):296-299.
Read abstract


Lepromatous leprosy in a renal transplant recipient.
Aytekin S, Yaşar Ş, Göktay F, et al. Am J Transplant.
2017 Apr 27.
Download PDF


The cross-cutting contribution of the end of neglected tropical diseases to the sustainable development goals.
Bangert M, Molyneux DH, Lindsay SW, et al. Infect Dis Poverty. 2017 Apr 4;6(1):73.
Download PDF


Leprosy in Children.
Barreto JG, Frade MAC, Bernardes Filho F, et al.
Curr Infect Dis Rep. 2017 Jun;19(6):23.
Read abstract


Functional Toll-Like Receptor (TLR)2 polymorphisms in the susceptibility to inflammatory bowel disease.
Bellon V, Brand S, Konrad A, et al. PLoS One. 2017 Apr 7;12(4):e0175180.
Download PDF


Structural and functional changes in the microcirculation of lepromatous leprosy patients - Observation using orthogonal polarization spectral imaging and laser Doppler flowmetry iontophoresis.
Bouskela E, Kraemer-Aguiar LG, Lupi O, et al. PLoS One. 2017 Apr 18;12(4):e0175743
Download PDF


History and mysteries of leprosy.
O'Brien C, Malik R. J Feline Med Surg. 2017 May;19(5):496-497.
Download PDF


Interruption of persistent exposure to leprosy combined or not with recent BCG vaccination enhances the response to Mycobacterium leprae specific antigens.
de Carvalho FM, Rodrigues LS, Duppre NC, PLoS Negl Trop Dis. 2017 May 3;11(5):e0005560.
Download PDF


Prevalence and risk factors for hepatitis B and C viruses in patients with leprosy.
Costa JEF, Morais VMS, Gonçales JP, et al. Acta Trop. 2017 Apr 27.
Read abstract


Assessment and comparison of liver functions in leprosy.
Dhavalshank GP, Dhavalshankh AG, Gaurkar S. Int J Cur Res Rev. 2017 
Download PDF


Comparing the sensitivity of auramine-rhodamine fluorescence to polymerase chain reaction in the detection of Mycobacterium leprae in Fite-negative tissue sections.
Elston DM, Liranzo MO, Scollard DM. J Am Acad Dermatol. 2017 May;76(5):992-993.
Read abstract


Trend of leprosy in individuals under the age of 15 in Mato Grosso (Brazil), 2001-2013.
Freitas BHBM, Cortela DDCB, Ferreira SMB. Rev Saude Publica. 2017 Apr 10;51:28.
Download PDF


Dapsone-associated fixed drug eruption.
Garcia D, Cohen PR. Expert Rev Clin Pharmacol.
2017 Apr 28:1-9.
Read abstract


A medical enigma : what "gale chinoise (Chinese scabies)" meant 150 years ago.
Gaüzere BA, Aubry P. Med Sante Trop. 2017 May 4.
Read abstract


Global practices in regard to implementation of preventive measures for leprosy.
Gillini L, Cooreman E, Wood T, et al. PLoS Negl Trop Dis. 2017 May 4;11(5):e0005399.
Download PDF


Strongyloides stercoralis hyperinfection: An often missed but potentially fatal cause of anemia and
hypoalbuminemia in leprosy patients on long-term steroid therapy.

Gupta V, Bhatia S, Mridha AR, et al. Indian J Dermatol Venereol Leprol. 2017 Mar 31.
Download PDF


Leprosy clinically masquerading as necrobiotic xanthogranuloma: a histopathological surprise!
Gupta V, Yadav D, Singh M, et al. Int J Dermatol. 2017 Apr 12.
Read abstract


PLOS Neglected Tropical Diseases: Ten years of progress in neglected tropical disease control and elimination … More or less.
Hotez P, Aksoy S. PLoS Negl Trop Dis. 2017 Apr 20;11(4):e0005355.
Download PDF


Remaining Challenges to Further Reduce the Leprosy Burden in Rajasthan.
Katoch K. RUHS Journal of Health Sciences. 2017 March;2(1):5-8.
Download PDF


Quinolone resistance-associated amino acid substitutions affect enzymatic activity of Mycobacterium leprae DNA gyrase.
Nakajima C, Suzuki Y, Yamaguchi T, et al. Biosci Biotechnol Biochem. 2017 Apr 18:1-5.
Read abstract


Correlation between therapy and lipid profile of leprosy patients: is there a higher risk for developing cardiovascular diseases after treatment?
Silva RVG, de Araújo RS, Aarão TLS, et al. Infect Dis Poverty. 2017 May 1;6(1):82.
Download PDF


Evaluation of agreement between tests for the diagnosis of leprosy.
Silva AR, Queiroz MFA, Ishikawa EAY, et al. J Bras Patol Med Lab. 2017.
Download PDF


Leprosy case detection campaign (LCDC) for active surveillance.
Thangaraju P, Venkatesan S, Showkath et al. Trop Doct. 2017 Jan 1.
Read abstract


Structural and functional changes in the microcirculation of lepromatous leprosy patients - Observation using orthogonal polarization spectral imaging and laser Doppler flowmetry iontophoresis.
Treu C, de Souza MDGC, Lupi O, et al. PLoS One. 2017 Apr 18;12(4):e0175743.
Download PDF


Severe type 1 upgrading leprosy reaction in a renal transplant recipient: a paradoxical manifestation associated with deficiency of antigen-specific regulatory T-cells?
Vieira AP, Trindade MAB, de Paula FJ, et al. BMC Infect Dis. 2017 Apr 24;17(1):305.
Download PDF


Quinolone resistance-associated amino acid substitutions affect enzymatic activity of Mycobacterium leprae DNA gyrase.
Yamaguchi T, Yokoyama K, Nakajima C, et al. Biosci Biotechnol Biochem. 2017 Apr 18:1-5.
Read abstract


Collaborating to develop joint water, sanitation and hygiene (WASH) and neglected tropical disease (NTD) sector monitoring: an expert consultation.
Waite RC, Woods G, Velleman Y, et al. Int Health. 2017 Apr 12:1-11.
Read abstract


Further evidence of leprosy in Isle of Wight red squirrels.
Vet Rec. 2017 Apr 22;180(16):407.
Read abstract

 

 

Journals & Newsletters

 

 

Community Eye Health Journal: http://www.cehjournal.org/

Disability, CBR & Inclusive Development: http://dcidj.org/

Hansenologia Internationalis: http://www.ilsl.br/revista/atual.php

Indian Journal of Leprosy: http://www.ijl.org.in/index.html 

Leprosy Review: https://www.lepra.org.uk/Pages/FAQs/Category/volume-88
Leprosy Review Repository (1928-2001) : http://leprev.ilsl.br/arquivo.php

Plos Neglected Tropical Diseases: http://journals.plos.org/plosntds/
 
Revista de Leprología:
http://www.leprosy-information.org/resource/revista-de-leprologia
 
WHO Goodwill Ambassador’s Newsletter for the elimination of leprosy:
http://www.leprosy-information.org/resource/who-goodwill-ambassador-s-newsletter-elimination-leprosy 

 

 

 

Websites & Services

 

 

 

InfoNTD - Information on cross-cutting issues in Neglected Tropical Diseases (NTDs) https://www.infontd.org/

LML - Leprosy Mailing List - a free moderated email list that allows all persons interested in this theme to share ideas, information, experiences and questions.
http://leprosymailinglist.blogspot.nl/

 

 


LML - S Deepak, B Naafs, S Noto and P Schreuder

LML blog link: http://leprosymailinglist.blogspot.it/

Contact: Dr Pieter Schreuder << editorlml@gmail.com

 


Virusvrij. www.avast.com